Detalhe da pesquisa
1.
Constitutional Microsatellite Instability, Genotype, and Phenotype Correlations in Constitutional Mismatch Repair Deficiency.
Gastroenterology
; 164(4): 579-592.e8, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586540
2.
Is HLA type a possible cancer risk modifier in Lynch syndrome?
Int J Cancer
; 152(10): 2024-2031, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36214792
3.
Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial.
Lancet
; 395(10240): 1855-1863, 2020 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32534647
4.
Sequencing-based microsatellite instability testing using as few as six markers for high-throughput clinical diagnostics.
Hum Mutat
; 41(1): 332-341, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471937
5.
A sensitive and scalable microsatellite instability assay to diagnose constitutional mismatch repair deficiency by sequencing of peripheral blood leukocytes.
Hum Mutat
; 40(5): 649-655, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30740824
6.
Response to 'Cutaneous squamous cell carcinoma is associated with Lynch syndrome: widening the spectrum of Lynch syndrome-associated tumours'.
Br J Dermatol
; 186(5): 913-914, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35322414
7.
Identification of people with Lynch syndrome from those presenting with colorectal cancer in England: baseline analysis of the diagnostic pathway.
Eur J Hum Genet
; 32(5): 529-538, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38355963
8.
GPs' willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a factorial randomised trial investigating factors influencing decisions.
Br J Gen Pract
; 73(729): e302-e309, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997217
9.
Cancer Prevention with Resistant Starch in Lynch Syndrome Patients in the CAPP2-Randomized Placebo Controlled Trial: Planned 10-Year Follow-up.
Cancer Prev Res (Phila)
; 15(9): 623-634, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35878732
10.
How Should We Test for Lynch Syndrome? A Review of Current Guidelines and Future Strategies.
Cancers (Basel)
; 13(3)2021 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33499123
11.
Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.
Lab Invest
; 89(1): 15-25, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19015642
12.
Mitochondrial DNA mutations in human colonic crypt stem cells.
J Clin Invest
; 112(9): 1351-60, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14597761
13.
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism.
FASEB J
; 20(12): 2009-16, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17012253
14.
Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR.
Nucleic Acids Res
; 30(14): e68, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12136116
15.
Changes in the human mitochondrial genome after treatment of malignant disease.
Mutat Res
; 525(1-2): 19-27, 2003 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12650902
16.
Angiotensin II-induced cardiomyocyte hypertrophy in vitro is TAK1-dependent and Smad2/3-independent.
Hypertens Res
; 35(4): 393-8, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072105
17.
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro.
In Vitro Cell Dev Biol Anim
; 47(2): 125-31, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21082279
18.
Somatic mitochondrial DNA deletions accumulate to high levels in aging human extraocular muscles.
Invest Ophthalmol Vis Sci
; 51(7): 3347-53, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20164450
19.
Motor neuron disease in a patient with a mitochondrial tRNAIle mutation.
Ann Neurol
; 59(3): 570-4, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16358336